产品货号:
Z33376
中文名称:
BCRP/ABCG2抗体
英文名称:
Anti-BCRP/ABCG2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BCRP/ABCG2 Antibody |
指标别名 | ABC15;ABCG2;ABCP;BCRP;ABCG2;BMDP;CD338;CDw338;EST157481;MRX;MXR;MXR1 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | ABCG2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human ABCG2 |
实际分子量 | 65~80KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ABCG2(Atp-binding cassette,subfamily g,member 2) also known as ABCP,BCRP or MRX,is a protein that in humans is encoded by the ABCG2 gene.The ABCG2 gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters,which are involved in the trafficking of biologic molecules across cell membranes.The ABCG2 protein is also a high capacity transporter for uric acid excretion in the kidney,liver,and gut.The ABCG2 gene is mapped on 4q22.1.In vitro assays of isolated membrane preparations revealed a high-capacity,vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.Ozvegy et al.(2001) concluded that ABCG2 is likely functioning as a homodimer or homooligomer in this expression system since it is unlikely that putative Sf9 transport partners would be overexpressed at similarly high levels.Abcg2 transports pheophorbide-a,which occurs in various plant-derived foods and food supplements and is highly efficient in limiting its uptake from ingested food.ABCG2 is a major factor in the concentrative transfer of drugs,carcinogens,and dietary toxins to the milk of mice,cows,and humans. |
Uniprot ID | Q9UNQ0 |
基因名全称 | ATP-binding cassette sub-family G member 2 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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